Alzheimer's Explained
Bridging Scientific Discovery and Everyday Care
Alzheimer's Research should be accessible and empowering, not confusing and overwhelming.
Alzheimer's Explained translates current scientific research papers and journals into everyday language.
How does ADE work?
Our Three Foundational Pillars
Knowledge
- Weekly Blog Posts breaking down the latest Alzheimer’s research
- Plain-language summaries of complex scientific
For casual readers who want a taste of science.
Understand
- Resource library for patients and caregivers
- Interactive games and visual learning tools
For those who want to deepen their understanding.
For those who want to deepen their understanding.
Connect
- Just found out your loved one has Alzheimer's? Start here.
- Guided articles tailored to each stage of the journey
For loved ones seeking support.
Alaina Yan
Student Advocate
Founder's Story
Meet the Founder
Alaina is currently a senior at Canyon Crest Academy. Her grandma was diagnosed with AD when she was just 10. Clueless to my grandma’s condition, she was baffled by the behavioral and cognitive decline she witnessed.
As she grew up and learned more about AD and other neurodegenerative disorders, she was concerned for her grandma; somebody she used to laugh and joke with now barely remembered what she said five minutes ago.
Thus, she threw herself into researching AD and its possible cures. Hope was instilled in her as she learned that everyday, scientists are getting closer and closer to fully understanding AD. However, throughout her research, she was constantly googling definitions and re-reading to understand the scientific jargon.
She wants to share her feelings of empowerment and hope to others impacted by AD. ADE was born. She hopes ADE can serve as a bridge between scientific AD research and uplift the people impacted by AD.
Irises symbolism of wisdom, truth, and courage embodies ADE's core pillars of knowledge, understanding, and connection. Named after Iris, the Greek goddess of the rainbow, they represent a bridge between worlds—a reflection of ADE's mission to connect scientific discovery with everyday life through accessible knowledge.
Top Articles
Can Advanced Alzheimer’s Be Reversed? What a New Mouse Study Found
Adapted from Chaubey et al’s paper “Pharmacologic reversal of advanced Alzheimer’s disease in mice and identification of potential therapeutic nodes in human brain” (Cell Reports Medicine, 2026)
Most of the current treatments and medications target the amyloid plaques and tau proteins. P7C3-A20, instead, works on rebalancing the brain’s NAD+ levels and preserving homeostasis. The success of P7C3-A20 has undermined the long-thought belief that AD is irreversible.
Brain size or brain tissue: exploring the role of early-life and late-life brain reserves in cognition
Article based on Han et al.’s paper Early- and late-life brain reserve proxies and their interactions with education on cognitive outcomes in older adults: A population-based MRI study
The scientists studied dementia-free adults aged 60+ in rural China. They filtered out those with dementia and other conditions with MRI scans. The scientists had picked this population as they wanted to study the importance of education to brain reserves.
They measured both early-life brain reserve and late-life; to measure early-life brain reserve, they used total intracranial volume (TIV) which estimates the brain size, head size, and acts as a benchmark to calculate the brain matter lost in neurodegenerative disorders.
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